The men’s Final Four isn’t necessarily close, but it’s not far either. Who is favored to be one of the last teams standing? Let’s check out the odds for the 2026 Final Four at DraftKings Sportsbook as of March 23. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports. To reach the Final Four 2026 East Region Duke: -125 (bet $10 to win $18 total)Michigan State: +475 (bet $10 to win $57.50 total)St. John’s: +475 (bet $10 to win $57.50 total)UConn: +500 (bet $10 to win $60 total) Midwest Region Michigan: -145 (bet $10 to win $16.90 total)Iowa State: +250 (bet $10 to win $35 total)Tennessee: +700 (bet $10 to win $80 total)Alabama: +1500 (bet $10 to win $160 total) South Region Houston: +130 (bet $10 to win $23 total)Illinois: +230 (bet $10 to win $33 total)Nebraska: +370 (bet $10 to win $47 total)Iowa: +750 (bet $10 to win $85 total) West Region Arizona: -160 (bet $10 to win $16.25 total)Purdue: +215 (bet $10 to win $31.50 total)Arkansas: +1000 (bet $10 to win $110 total)Texas: +2500 (bet $10 to win $260 total) Here’s what to know about the Final Four oddsboard: The Favorite(s): Three 1-seeds — Duke, Arizona and Michigan — are favored to make the Final Four, along with one 2-seed in Houston, after defending champion Florida was bounced in the Round of 32. Now we know we won’t have a repeat of last season, where all four 1-seeds made it to the national semifinals. Arizona last made the Final Four way back in 2001, while Michigan last made it in 2018. The Blue Devils last made a Final Four appearance last season. Regions to Watch: With Florida’s loss, the South Region is essentially up for grabs. While Houston is favored to win it, Illinois and Nebraska aren’t far behind from an odds perspective. The Cougars get the Illini next, while the Cornhuskers face Big Ten foe Iowa. There is also that treacherous East Region, which features Michigan State, St. John’s and UConn behind Duke on the oddsboard. The Blue Devils will have to get past the Red Storm and the winner of UConn-MSU in order to make it to the Final Four.
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